A continuously updated blog post on the effects of tobacco and modern additives to human brain/bodies.
I really don't understand why there isn't a huge debate about a reevaluation of all drugs under the guidelines of modern drug research instead of this "legalize everything" debate. Stuff like Krokodil (see some effects after usage, even once or a few times at the google image search but be advised: very graphic ..) just isn't anything you should offer to try even under the assumption that people are behaving rational.
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